Page 7 - EngineerIt February 2021
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Prof Suprakas Sihna Ray


                                                                                 thinner than the diameter of a single
                                                                                 human hair. It is finding application in
        One of the sensors developed at the CSIR Nanotechnology Centre. The sensor is used  transport, medicine, electronics,
        in the breath analysis system to simplify the measurement of glucose levels in the  energy, defence, and desalination.
        management of diabetic patients                                          The range of industries where
                                                                                 graphene research is making an
                                                                                 impact is substantial. “The potential of
        patients. One’s breath may have a high  Graphene, the wonder carbon      graphene is limited only by our
        concentration of acetone which is a  Researchers at the CeNAM are also   imagination,” Prof Ray said.
        warning sign that diabetes is not under  working on Graphene, which is an   Another area of research of the
        good control. If not treated immediately  allotrope of carbon consisting of a single  CeNAM is in bio plastics and the
        with insulin, the ketone build-up can  layer of atoms arranged in a two-  development of new plastic materials
        progress to a dangerous condition    dimensional honeycomb lattice. The  that are stronger, yet biodegradable. The
        known as diabetic ketoacidosis, and  name is a combination of "graphite" and  CeNAM has established an extensive
        even a diabetic coma.                the suffix -ene, reflecting the fact that  network with key local and international
           “We have come a long way in the   the graphite allotrope of carbon consists  organisations. With nanotechnology
        development of the breath analyser”, Prof  of stacked graphene layers.   being such a specialised field, the centre
        Suprakas Sihna Ray told EngineerIT. “We  Graphene is many times stronger  has partnered with several universities
        are now at the industrialisation stage of  than steel, yet incredibly lightweight  to develop human capital and has
        the breath analyser and are supporting  and flexible. It is electrically and  trained more than 130 post-doctoral
        the consortium that will ultimately  thermally conductive but also       fellows, PHD and Master’s students
        manufacture and market the device. The  transparent. It is often described as the  since the centre opened in 2007.
        development of complex medical devices  world's first two-dimensional (2D)  Currently the CeNAM employs close to
        can take between six and seven years. It  material and is one million times  100 researchers.           n
        requires extensive trial periods before the
        product can be registered by the South
                                              The ideas and concepts behind nanoscience and nanotechnology started with a talk
        African Health Products Regulatory
                                              entitled “There’s plenty of room at the bottom” by physicist Richard Feynman at an
        Authority. (SAHPRA)
                                              American Physical Society meeting at the California Institute of Technology (CalTech) on
           The outflow of work on the breath
                                              29 December 1959, long before the term nanotechnology was used. In his talk, Feynman
        analyser has found its way into other
                                              described a process through which scientists would be able to manipulate and control
        products, such as the delivery of active
                                              individual atoms and molecules. Over a decade later, in his explorations of ultra-
        ingredients in cosmetic products to
                                              precision machining, Professor Norio Taniguchi coined the term nanotechnology;
        increase their efficacy. “We are also
                                              however it wasn’t until 1981, with the development of microscopes that could “see”
        working on delivery systems for
                                              individual atoms, that modern nanotechnology began.
        medicines and the enhancement of time
                                                It is difficult to imagine how small nanotechnology really is. One nanometre is a
        release drug delivery systems to reduce
                                              billionth of a metre (or 10-9 of a metre). Nanoscience and nanotechnology involve the
        the number of times a medication has to
                                              ability to see and control individual atoms and molecules. About 30 years ago, the
        be taken each day. This will increase
                                              development of the scanning tunnelling microscope (STM) and the atomic force
        patient compliance, particularly
                                              microscope (AFM) unlocked the age of nanotechnology enabling scientists and engineers
        important in the treatment of TB and HIV
                                              to explore a wide variety of ways to deliberately make materials at the nano-scale to
        infections. We are continuing our work
                                              take advantage of their enhanced properties such as higher strength, lighter weight,
        on the breath analyser to ultimately
                                              increased control of the light spectrum, and greater chemical reactivity than their larger-
        include the detection of other conditions
                                              scale counterparts.                                              n
        such as cancer, for example.”
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